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Location: Tyler Synced from ClinicalTrials.gov · August 08, 2026

Clinical studies recruiting near Tyler

Studies with at least one listed site matching this location on the public registry. Each page explains the study in plain language, with locations and study-team contacts. Clinicians: generate a printable list for your patient →

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Phase 1 · University of Texas at Tyler · Erasca, Inc. · NCT06983743
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Phase 3 · USO - Texas Oncology - Northeast Texas · Eli Lilly and Company · NCT07218380
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
Phase 3 · Daiichi Sankyo · NCT07022483
Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
NA · Christus Trinity Mother Frances Health System-Hospital · Boston Scientific Corporation · NCT07575269
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line
Phase 3 · Texas Oncology - Northeast Texas ( Site 8012) · Merck Sharp & Dohme LLC · NCT06136559
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Phase 3 · The University of Texas Health Science Center at Tyler dba U · Merck Sharp & Dohme LLC · NCT06393374
A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer
Phase 3 · Texas Oncology, P.A. - Tyler · BioNTech SE · NCT07365995
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Can
Phase 2 · Texas Oncology - Tyler · Aadi Bioscience, Inc. · NCT05997017
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carbop
Phase 3 · University of Texas Health Center at Tyler · Hoffmann-La Roche · NCT06793215
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Phase 3 · Clinical Study Site · Summit Therapeutics · NCT07228832
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Phase 2 · Tyler Research Institute · Eli Lilly and Company · NCT07415044
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintena
Phase 3 · Texas Oncology - Northeast Texas ( Site 8002) · Merck Sharp & Dohme LLC · NCT07216703
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Phase 3 · The University of Texas Health Science Center at Tyler · Janssen Research & Development, LLC · NCT07499232
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Phase N/A · Texas Oncology - Tyler · Agendia · NCT03053193
SELUTION4BTK Trial
NA · Christus Health · M.A. Med Alliance S.A. · NCT05055297
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previ
Phase 3 · Texas Oncology-Northeast Texas · Pfizer · NCT07144280
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcera
Phase 3 · Tyler Research Institute · Eli Lilly and Company · NCT06937086
Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma
Phase 2 · Texas Oncology - Northeast Texas · SCRI Development Innovations, LLC · NCT05972135
A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in Fi
Phase 3 · University of Texas Health Science Center at Tyler · Amgen · NCT07005128
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
Phase 1 · Texas Oncology, P.A. - Oncology · Bristol-Myers Squibb · NCT05245500
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Phase 4 · Tyler Research Institute, LLC · Takeda · NCT06095128
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung C
Phase 3 · The University of Texas Health Science Center at Tyler dba U · Merck Sharp & Dohme LLC · NCT06623422
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Phase 2 · Tyler Research Institute, LLC · Takeda · NCT06764615
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesop
Phase 3 · Texas Oncology, P.A. - Tyler · Daiichi Sankyo · NCT06731478
Study for Subjects With Relapsed/Refractory Non- Hodgkin Lymphoma
Phase 1 · Texas Oncology · ImmunityBio, Inc. · NCT05618925
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-
Phase 2 · The University of Texas Health Science Center at Tyler dba U · Merck Sharp & Dohme LLC · NCT06890884
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of
Phase 3 · Research Site · AstraZeneca · NCT06921785
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not
Phase 3 · Tyler, TX Investigative Site FIN-10422 · Colorado Prevention Center · NCT06033950
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Sta
Phase 3 · The University of Texas Health Science Center at Tyler dba U · Bristol-Myers Squibb · NCT06561386
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
Phase 3 · Research Site · AstraZeneca · NCT05952557
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