Condition: Cervical Cancer · Sponsor: Merck Sharp & Dohme LLC
Researchers are looking for new ways to treat metastatic cervical cancer. Cervical cancer is cancer in the cervix, the lower part of the uterus (womb). Metastatic means the cancer has spread to other parts of the body. Researchers want to learn about giving the study medicine sacituzumab tirumotecan (also called sac-TMT or MK-2870) along with pembrolizumab and bevacizumab treatments. Sac-TMT is an antibody drug conjugate, which is a type of medicine that attaches to specific targets on cancer cells and delivers treatment to destroy those cells. The goals of this study are to learn: * About the safety of sac-TMT with pembrolizumab and bevacizumab, and if people tolerate them when given together, and * If people who receive sac-TMT and pembrolizumab, with or without bevacizumab, live longer overall or without their cancer getting worse as compared to those who receive standard treatment
This description comes directly from the study's public registry record.
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| Florida Cancer Specialists - South ( Site 7001) | Fort Myers, Florida, United States | Recruiting |
| Mount Sinai Comprehensive Cancer Center ( Site 5043) | Miami Beach, Florida, United States | Recruiting |
| Mount Sinai Comprehensive Cancer Center ( Site 6000) | Miami Beach, Florida, United States | Recruiting |
| Florida Cancer Specialists - East ( Site 7000) | West Palm Beach, Florida, United States | Recruiting |
| Winship Cancer Institute of Emory University ( Site 5005) | Atlanta, Georgia, United States | Recruiting |
| Nancy N. & J.C. Lewis Cancer and Research Pavillion - Research Department ( Site 6005) | Savannah, Georgia, United States | Recruiting |
| TRIALS 365 ( Site 6008) | Shreveport, Louisiana, United States | Recruiting |
| Minnesota Oncology Hematology, PA ( Site 8003) | Edina, Minnesota, United States | Recruiting |
| Women's Cancer Center of Nevada ( Site 6011) | Las Vegas, Nevada, United States | Recruiting |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 6009) | New York, New York, United States | Recruiting |
| Oklahoma Cancer Specialists and Research Institute, LLC ( Site 6001) | Tulsa, Oklahoma, United States | Recruiting |
| Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute) (WVCI) ( Site 8007) | Eugene, Oregon, United States | Recruiting |
+ 143 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07216703