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Study identifier: NCT06937086 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Condition: Ulcerative Colitis · Obesity or Overweight  ·  Sponsor: Eli Lilly and Company

PhasePhase 3
Planned participants350
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo, leads to decrease or disappearance of UC symptoms, and loss of at least one-tenth of the overall body weight. Participation in this study will last up to 61 weeks, including 52 weeks of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (189)

Digestive Health SpecialistsDothan, Alabama, United StatesRecruiting
Smart Cures Clinical ResearchAnaheim, California, United StatesRecruiting
Cedars-Sinai Medical CenterBeverly Hills, California, United StatesNot Yet Recruiting
United Medical Doctors - Los AlamitosLos Alamitos, California, United StatesRecruiting
California Medical Research AssociatesNorthridge, California, United StatesRecruiting
Research Associates of South Florida - Miami - Southwest 8th StreetMiami, Florida, United StatesRecruiting
Gastro Health Research - MiamiMiami, Florida, United StatesRecruiting
Orlando HealthOrlando, Florida, United StatesRecruiting
Digestive and Liver Center of FloridaOrlando, Florida, United StatesRecruiting
Gastro Health Research - PensacolaPensacola, Florida, United StatesRecruiting
Precision Clinical ResearchSunrise, Florida, United StatesRecruiting
Grand Teton Research GroupIdaho Falls, Idaho, United StatesRecruiting

+ 177 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06937086