EICHORCondition: Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma · Sponsor: Merck Sharp & Dohme LLC
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
The goal of this study is to evaluate nemtabrutinib compared with investigator's choice of ibrutinib or acalabrutinib in participants with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who have not received any prior therapy. The primary hypotheses are that (1) nemtabrutinib is non-inferior to ibrutinib or acalabrutinib with respect to objective response rate (ORR) per International Workshop on Chronic Lymphocytic Leukemia (iwCLL) Criteria 2018 by blinded independent central review (BICR) and (2) nemtabrutinib is superior to ibrutinib or acalabrutinib with respect to progression free survival (PFS) per iwCLL Criteria 2018 by BICR.
This description comes directly from the study's public registry record.
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Always discuss trial participation with your own doctor first.
| USA Mitchell Cancer Institute ( Site 0014) | Mobile, Alabama, United States | Recruiting |
| Banner MD Anderson Cancer Center ( Site 0059) | Gilbert, Arizona, United States | Recruiting |
| Banner MD Anderson Cancer Center - University Medical Center Phoenix ( Site 0051) | Phoenix, Arizona, United States | Recruiting |
| Arizona Oncology Associates - NAHOA ( Site 8007) | Prescott, Arizona, United States | Completed |
| Alta Bates Summit Medical Center ( Site 0004) | Berkeley, California, United States | Active Not Recruiting |
| Moores Cancer Center ( Site 0003) | La Jolla, California, United States | Recruiting |
| Care Access - South Pasadena ( Site 0070) | Pasadena, California, United States | Recruiting |
| Saint Joseph Hospital ( Site 0026) | Denver, Colorado, United States | Recruiting |
| Lutheran Medical Center ( Site 0027) | Golden, Colorado, United States | Recruiting |
| Intermountain Health St. Mary's Regional Hospital ( Site 0025) | Grand Junction, Colorado, United States | Recruiting |
| Eastern CT Hematology & Oncology Associates ( Site 0033) | Norwich, Connecticut, United States | Recruiting |
| Lynn Cancer Center at Boca Raton Regional Hospital ( Site 0063) | Boca Raton, Florida, United States | Recruiting |
+ 189 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06136559