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Study identifier: NCT05245500 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Condition: Mesothelioma · Non Small Cell Lung Cancer · Malignant Peripheral Nerve Sheath Tumors  ·  Sponsor: Bristol-Myers Squibb

PhasePhase 1
Planned participants336
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid tumor malignancy with homozygous deletion of the MTAP gene.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain the NCT# and Site #.

Always discuss trial participation with your own doctor first.

Locations (25)

Mayo ClinicPhoenix, Arizona, United StatesRecruiting
Sarah Cannon Research Institute (SCRI) - HealthONE LocationDenver, Colorado, United StatesRecruiting
Rocky Mountain Cancer Centers, LLP - OncologyLone Tree, Colorado, United StatesRecruiting
Mayo ClinicJacksonville, Florida, United StatesRecruiting
Sarah Cannon Research Institute at Florida Cancer SpecialistsOrlando, Florida, United StatesRecruiting
Local Institution - 124Chicago, Illinois, United StatesWithdrawn
Dana-Farber Cancer InstituteBrookline, Massachusetts, United StatesRecruiting
Cancer and Hematology Centers of Western MichiganNorton Shores, Michigan, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Rutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, United StatesRecruiting
Local Institution - 129Mineola, New York, United StatesNot Yet Recruiting
David H Koch, Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

+ 13 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT05245500