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Location: Springfield Synced from ClinicalTrials.gov · August 07, 2026

Clinical studies recruiting near Springfield

Studies with at least one listed site matching this location on the public registry. Each page explains the study in plain language, with locations and study-team contacts. Clinicians: generate a printable list for your patient →

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Phase 3 · Oncology Hematology Associates · Eli Lilly and Company · NCT07218380
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
NA · Baystate Medical Center · Analog Device, Inc. · NCT05650541
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Wi
Phase 2 · Southern Illinois University School of Medicine · National Cancer Institute (NCI) · NCT05564390
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed
Phase 3 · Southern Illinois University School of Medicine · National Cancer Institute (NCI) · NCT06172296
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Phase 3 · Clinvest Headlands LLC · Kallyope Inc. · NCT07674654
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small C
Phase 3 · Southern Illinois University School of Medicine · NRG Oncology · NCT05624996
Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma
NA · Southern Illinois University · Case Comprehensive Cancer Center · NCT06262516
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated C
Phase 3 · Southern Illinois University School of Medicine · Alliance for Clinical Trials in Oncology · NCT07321652
Randomization of Single vs Multiple Arterial Grafts
NA · Baystate Health · Weill Medical College of Cornell University · NCT03217006
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Phase 2/Phase 3 · Southern Illinois University School of Medicine · National Cancer Institute (NCI) · NCT05691478
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiov
Phase 3 · Prarie Education and Research · Amgen · NCT07037433
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
Phase 1/Phase 2 · Oncology Associates of Oregon, P.C. · Pfizer · NCT07421700
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Phase 3 · Clinical Study Site · Summit Therapeutics · NCT07228832
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Phase 2 · Springfield Clinic - First · Eli Lilly and Company · NCT07415044
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
NA · Southern Illinois University School of Medicine · Alliance for Clinical Trials in Oncology · NCT07091617
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS
Phase 3 · Springfield Clinic Main Campus · Eli Lilly and Company · NCT06890598
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
Phase N/A · Mercy Clinic Springfield Communities · PrECOG, LLC. · NCT06538038
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Phase N/A · Mercy Medical Center · Agendia · NCT03053193
Aim 2 - Conversations Can Save Lives: TALKing About Buprenorphine & Methadone for Opioid Use Treatment Initiation
NA · Baystate Medical Center · Baystate Medical Center · NCT06527820
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
Phase 2 · Southern Illinois University School of Medicine · Children's Oncology Group · NCT04322318
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Phase 3 · Southern Illinois University School of Medicine · NRG Oncology · NCT05946213
Collection of Samples USOPTIVAL Study
Phase N/A · Springfield Clinic · Universal Diagnostics · NCT04792684
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
Phase 2 · Oregon Urology Institute · CG Oncology, Inc. · NCT06567743
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Phase 2 · Clinvest Research LLC · Eli Lilly and Company · NCT05986292
Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
Phase 4 · Southern Illinois University School of Medicine · Southern Illinois University · NCT06492512
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Phase 2/Phase 3 · Southern Illinois University School of Medicine · NRG Oncology · NCT05174169
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Canc
Phase 3 · Southern Illinois University School of Medicine · Alliance for Clinical Trials in Oncology · NCT06632327
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastati
Phase 3 · Southern Illinois University School of Medicine · Alliance for Clinical Trials in Oncology · NCT06931340
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-
Phase 3 · Mercy Hospital Springfield · NRG Oncology · NCT06500481
A Type I Hybrid Effectiveness-Implementation Trial of MIO
NA · Baystate Medical Center · Baystate Medical Center · NCT07168642
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