Condition: Urothelial Carcinoma · Sponsor: Case Comprehensive Cancer Center
The goal of this study is to conduct the first randomized-controlled trial to determine the oncologic efficacy of lymph node dissection in participants with upper tract urothelial cell carcinoma. The main questions it aims to answer are: * To determine oncologic outcomes, specifically 2-year recurrence-free survival * To determine other oncologic outcomes including treatment-free, cancer-specific and overall survival * To determine time to recurrence and recurrence patterns * To determine use of adjuvant therapies * To determine perioperative complications Participants will undergo nephroureterectomy with or without lymph node dissection. Researchers will compare these two groups to determine the oncologic efficacy of performing lymph node dissection.
This description comes directly from the study's public registry record.
Mohamed Eltemamy, MD · 216-444-5888 · Eltemam@ccf.org
Rebecca Campbell, MD · 216-444-1105 · CAMPBER7@ccf.org
Always discuss trial participation with your own doctor first.
| University of Florida Health Science Center | Gainesville, Florida, United States | Recruiting |
| Southern Illinois University | Springfield, Illinois, United States | Recruiting |
| University Hospitals Cleveland Medical Center, Urology Institute, Case Comprehensive Cancer Center | Cleveland, Ohio, United States | Recruiting |
| Cleveland Clinic Glickman Urological and Kidney Institute | Cleveland, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06262516