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Condition: Advanced Sarcoma Synced from ClinicalTrials.gov · August 07, 2026

Recruiting studies: Advanced Sarcoma

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

A Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adult
Phase 1 · 1 location(s) · Antonio Pérez Martínez · NCT06087341
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
Phase 2 · 2 location(s) · Sarcoma Alliance for Research through Collaboration · NCT06942442
Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcom
Phase 2 · 2 location(s) · M.D. Anderson Cancer Center · NCT05019703
Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas
Phase 1 · 1 location(s) · Tcelltech Inc. · NCT07052383
Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas
Phase 2 · 1 location(s) · Asociación Europea y Latinoamericana SELNET para la Investig · NCT07032285
Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors
Phase 2 · 1 location(s) · National Cancer Institute (NCI) · NCT06176989
Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Phase 1/Phase 2 · 1 location(s) · Second Affiliated Hospital of Guangzhou Medical University · NCT05187338
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
Phase 1 · 3 location(s) · BioEclipse Therapeutics · NCT04282044
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangement
Phase 1/Phase 2 · 165 location(s) · Turning Point Therapeutics, Inc. · NCT03093116
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Gra
Phase 2 · 22 location(s) · Centre Leon Berard · NCT03624244
Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer
Phase 1/Phase 2 · 1 location(s) · Essen Biotech · NCT07067255
Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma
Phase 2 · 1 location(s) · Gabriel Tinoco · NCT06528769
KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC)
Phase 2 · 38 location(s) · Merck Sharp & Dohme LLC · NCT07252739
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
Phase 1 · 25 location(s) · Bristol-Myers Squibb · NCT05245500
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
Phase 1/Phase 2 · 26 location(s) · Tango Therapeutics, Inc. · NCT05732831
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
Phase 2 · 1 location(s) · HRYZ Biotech Co. · NCT06277154
MAGNATE-S: Paclitaxel Polymer Micelles Combo in Advanced Sarcoma
Phase 2 · 1 location(s) · Shanghai 6th People's Hospital · NCT07359053
Ivonescimab in the Treatment of Multiple Advanced Tumors
Phase 2 · 1 location(s) · Fudan University · NCT06683846
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Phase 1/Phase 2 · 68 location(s) · Turning Point Therapeutics, Inc. · NCT04094610
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
Phase 1/Phase 2 · 1 location(s) · Memorial Sloan Kettering Cancer Center · NCT04577014
T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissu
Phase 1 · 1 location(s) · M.D. Anderson Cancer Center · NCT06474676
Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma
Phase 2 · 1 location(s) · M.D. Anderson Cancer Center · NCT07283731
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
Phase 2 · 1 location(s) · M.D. Anderson Cancer Center · NCT04771520
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Phase 2 · 4 location(s) · Medical College of Wisconsin · NCT04040205
A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors
Phase 1 · 1 location(s) · GONGCHU Biotechnology Co., Ltd · NCT06508307
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)
Phase 2 · 11 location(s) · Asociación Europea y Latinoamericana SELNET para la Investig · NCT06114004
Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive
Phase 1 · 1 location(s) · Fred Hutchinson Cancer Center · NCT07227571
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional
Phase 1/Phase 2 · 11 location(s) · GI Innovation, Inc. · NCT05824975
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Phase 1 · 7 location(s) · Daiichi Sankyo · NCT06644755
Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Adv
Phase 1 · 16 location(s) · National Cancer Institute (NCI) · NCT05711615
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