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Study identifier: NCT04577014 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Condition: Soft Tissue Sarcoma · Sarcoma,Soft Tissue · Sarcoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1/Phase 2
Planned participants98
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being done to find out whether the study drug Retifanlimab, a monoclonal antibody against the PD-1 protein, combined with gemcitabine and docetaxel, is a safe and effective treatment for your disease. Gemcitabine and docetaxel are chemotherapy drugs that are commonly used to treat soft tissue sarcoma. Retifanlimab is an experimental drug that boosts the immune system's ability to fight cancer cells. The study researchers think that Retifanlimab may help gemcitabine and docetaxel work better against soft tissue sarcoma that is either locally advanced or has spread beyond its original location (metastasized), and it cannot be removed with surgery (unresectable).

This description comes directly from the study's public registry record.

Talk to the study team

Sandra D'Angelo, MD  ·  646-888-4159  ·  zzPDL_MED_Sarcoma_Clinical_Trials@mskcc.org

William Tap, MD  ·  646-888-4163  ·  zzPDL_MED_Sarcoma_Clinical_Trials@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04577014