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Condition: Treatment Resistant Major Depression Synced from ClinicalTrials.gov · August 08, 2026

Recruiting studies: Treatment Resistant Major Depression

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive D
NA · 1 location(s) · Polytechnic Institute of Porto · NCT07474974Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
Phase 1 · 2 location(s) · Texas A&M University · NCT06480201Establishing Mobile Transcranial Magnetic Stimulation
Phase 4 · 1 location(s) · Medical University of South Carolina · NCT06748209RESISTance Exercise for Depression Trial
NA · 2 location(s) · University of Wisconsin, Madison · NCT06110897E-field Guided iTBS for Treatment Resistant Depression
NA · 2 location(s) · Centre for Addiction and Mental Health · NCT05583747Intravenous Ketamine for Treatment-Resistant Depression
Phase 2 · 1 location(s) · Mayo Clinic · NCT06668571Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression
NA · 1 location(s) · Charles University, Czech Republic · NCT07324070Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst St
NA · 1 location(s) · Ataturk University · NCT07264452Natural History of Depression, Bipolar Disorder and Suicide Risk
Phase N/A · 1 location(s) · National Institute of Mental Health (NIMH) · NCT06462196i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Tri
Phase 2 · 1 location(s) · University Health Network, Toronto · NCT06480500Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
NA · 1 location(s) · Sunnybrook Health Sciences Centre · NCT05813093A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Trea
Phase 2 · 48 location(s) · atai Therapeutics, Inc. · NCT06524830Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
NA · 1 location(s) · Andrew Krystal · NCT07127913Ketamine Augmentation of ECT in Treatment-Resistant Depression
Phase 3 · 1 location(s) · Università Vita-Salute San Raffaele · NCT07088380Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation
NA · 1 location(s) · West China Hospital · NCT06542094Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resi
Phase 2 · 1 location(s) · National Institute of Mental Health (NIMH) · NCT06511908EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorde
Phase N/A · 1 location(s) · Istanbul University - Cerrahpasa · NCT07748091Accelerated TMS for Treatment-Resistant ECT
NA · 1 location(s) · Universitair Ziekenhuis Brussel · NCT07115628Brain Stimulation for Severe Depression
NA · 2 location(s) · Inner Cosmos Inc · NCT05393622qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
Phase 1 · 2 location(s) · Sunnybrook Health Sciences Centre · NCT06719427Lumateperone for Late-Life Depression
Phase 3 · 2 location(s) · Eric Lenze · NCT07623135Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus
NA · 1 location(s) · University Hospital, Grenoble · NCT04296097Closed-Loop Deep Brain Stimulation for Major Depression
NA · 1 location(s) · Andrew Krystal · NCT04004169Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Phase N/A · 1 location(s) · Unity Health Toronto · NCT06732089Comorbid Obesity and Depression With an Anti-inflammatory Medication
NA · 1 location(s) · King's College London · NCT06537921Biomarker-guided rTMS for Treatment Resistant Depression
Phase 3 · 2 location(s) · Weill Medical College of Cornell University · NCT04041479The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Us
Phase 3 · 12 location(s) · Dr. Inge Winter · NCT05973851Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression
Phase N/A · 1 location(s) · Max-Planck-Institute of Psychiatry · NCT06396312NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Phase 1 · 1 location(s) · Washington University School of Medicine · NCT02994433ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
Phase N/A · 2 location(s) · Salma Health, Inc. · NCT07528014
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.