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Study identifier: NCT06732089 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study

Condition: Major Depressive Disorder (MDD) · Major Depressive Episode · Treatment-Resistant Major Depressive Disorder  ·  Sponsor: Unity Health Toronto

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to learn about remote mental health monitoring technology for adults with treatment-resistant depression. The main question it aims to answer is: are digital mental health monitoring tools (an electronic data capture platform and wearable device (e.g., smartwatch or smart-ring)) feasible to implement alongside clinical treatment for depression? The secondary aim of this study is to inform preliminary clinical parameters for larger, definitive studies. Participants receiving neuropsychiatric treatment (repetitive transcranial magnetic stimulation, intravenous ketamine, or electroconvulsive therapy) as part of their regular medical care for treatment-resistant depression in the Interventional Psychiatry Program will have their clinical assessment data entered into a digital platform and will wear an accessory-based wearable device for the duration of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Dr. Venkat Bhat, M.D., F.R.C.P.C.  ·  416-360-4000  ·  venkat.bhat@unityhealth.to

Dr. Karisa Parkington, Ph.D.  ·  416-360-4000  ·  karisa.parkington@unityhealth.to

Always discuss trial participation with your own doctor first.

Locations (1)

St. Michael's Hospital, Unity Health TorontoToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06732089