Condition: Depressive Disorder, Treatment-Resistant · Treatment Resistant Depression (TRD) · Sponsor: Mayo Clinic
The purpose of this study is to to evaluate the relationships between peak (% change from baseline) central GABA and Glu levels during a 40-min IV ketamine or normal saline infusion utilizing fMRS, and change in peripheral GABA and Glu levels from baseline to 24-hr postinfusion utilizing LCMS, with baseline to 24-hr post-infusion change in depression (MADRS) in 30 TRD adults.
This description comes directly from the study's public registry record.
Nicole Reinicke · 507-422-1835 · reinicke.nicole@mayo.edu
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| Mayo Clinic in Rochester | Rochester, Minnesota, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06668571