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Condition: Treatment Resistant Depression Trd Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Treatment Resistant Depression Trd

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Intravenous Ketamine for Treatment-Resistant Depression
Phase 2 · 1 location(s) · Mayo Clinic · NCT06668571DBS for Depression
Phase 1 · 1 location(s) · Northwell Health · NCT06096207A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Thera
NA · 101 location(s) · LivaNova · NCT03887715taVNS or TMS or Both for Depression
NA · 1 location(s) · Medical University of South Carolina · NCT05725239Accelerated iTBS for Major Depression
NA · 1 location(s) · Istanbul University - Cerrahpasa · NCT07603804Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
NA · 2 location(s) · Massachusetts General Hospital · NCT07563868Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
Phase N/A · 5 location(s) · Riccardo Guglielmo · NCT07146503IV Ketamine vs. IN Esketamine for MDD TRD
Phase N/A · 1 location(s) · Gustavo Vazquez · NCT06488586Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
NA · 1 location(s) · Joao L. DeQuevedo · NCT04080778Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst St
NA · 1 location(s) · Ataturk University · NCT07264452Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Phase N/A · 1 location(s) · Senz · NCT07706478Ketamine Augmentation of ECT in Treatment-Resistant Depression
Phase 3 · 1 location(s) · Università Vita-Salute San Raffaele · NCT07088380Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression
Phase 4 · 1 location(s) · Aalborg University Hospital · NCT07080723ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Phase 2 · 48 location(s) · Alto Neuroscience · NCT07553637Personalized DBS Targeting for Treating Depression
EARLY_Phase 1 · 1 location(s) · Second Affiliated Hospital, School of Medicine, Zhejiang Uni · NCT06784388DBS for TRD With the Medtronic Percept PC
NA · 1 location(s) · Helen Mayberg, MD · NCT05773755Treatment Resistant Depression and Vagus Nerve Stimulation
NA · 24 location(s) · Assistance Publique - Hôpitaux de Paris · NCT05952674Translational Biomarkers in Accelerated Neuromodulation for Treatment-resistant Depression
NA · 1 location(s) · ITAB - Institute for Advanced Biomedical Technologies · NCT05798143Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression
NA · 1 location(s) · The Royal Ottawa Mental Health Centre · NCT06773949Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression
NA · 1 location(s) · Sunnybrook Health Sciences Centre · NCT07094789Physical Activity Program for TRD
NA · 1 location(s) · Unity Health Toronto · NCT06404320COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant Depression
NA · 3 location(s) · Danish Research Centre for Magnetic Resonance · NCT06895863Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression
NA · 1 location(s) · Charles University, Czech Republic · NCT07324070Esketamine With or Without Integration Therapy for Treatment-Resistant Depression
Phase 4 · 2 location(s) · University of Puerto Rico · NCT07369102Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety S
NA · 1 location(s) · University of California, San Diego · NCT07217223Cannabidiol Oil for Treatment-Resistant Major Depression
Phase 1/Phase 2 · 1 location(s) · Universidade do Sul de Santa Catarina · NCT07696871Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation
NA · 1 location(s) · West China Hospital · NCT06542094ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
Phase N/A · 2 location(s) · Salma Health, Inc. · NCT07528014A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression
Phase 4 · 6 location(s) · Janssen Korea, Ltd., Korea · NCT07053345A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression.
Phase N/A · 18 location(s) · LivaNova · NCT03320304
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.