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Study identifier: NCT06096207 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DBS for Depression

Condition: Treatment Resistant Depression  ·  Sponsor: Northwell Health

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to demonstrate the feasibility and safety of deep brain stimulation in treatment resistant depression. The main questions it aims to answer are: * Is deep brain stimulation effective in treating treatment resistant depression? * Does deep brain stimulation improve overall clinical well-being and functioning? Participants will be implanted with a deep brain stimulation device. They will then be monitored over a 5-year period by using multiple questionnaires to track their depression symptoms. The device will be turned off at certain time points, unbeknown to the participant, to show the efficacy of the device when it is turned on. The device will be ON for 8.5 months and OFF for 3.5 months during the first year. Researchers will compare questionnaire scores when the device is off versus on to see if the device is working in reducing depression.

This description comes directly from the study's public registry record.

Talk to the study team

Samantha Gonzalez  ·  7184704152  ·  sgonzalez30@northwell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Zucker Hillside HospitalQueens, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06096207