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Study identifier: NCT07053345 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Condition: Depressive Disorder, Treatment-Resistant  ·  Sponsor: Janssen Korea, Ltd., Korea

PhasePhase 4
Planned participants47
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate how well esketamine nasal spray works in improving depressive symptoms in participants with treatment resistant depression (TRD). This will be assessed by the change from baseline in the Hamilton depression rating scale (HAM-D; 17-item) total score from Day 1 (baseline) to the end of the 4-week treatment phase (Day 28).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (6)

Cha Ilsan Medical CenterGoyang Si Gyeonggi Do, South KoreaRecruiting
Wonkwang University HospitalIksan, South KoreaRecruiting
Kangbuk Samsung HospitalSeoul, South KoreaRecruiting
Asan Medical CenterSeoul, South KoreaRecruiting
Samsung Medical CenterSeoul, South KoreaRecruiting
Kyung Hee University HospitalSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07053345