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Study identifier: NCT03320304 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression.

Condition: Treatment Resistant Depression  ·  Sponsor: LivaNova

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this study is to assess short, mid and long-term clinical outcomes in patients with difficult to treat depression (such as patients with treatment resistant depression) treated with Vagus Nerve Stimulation (VNS) Therapy as adjunctive therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Funda Basdar  ·  +32 473 97 49 41  ·  funda.basdar@livanova.com

Gaia Giannicola  ·  Gaia.Giannicola@livanova.com

Always discuss trial participation with your own doctor first.

Locations (18)

AKH Allgemeines Krankenhaus der Stadt WienVienna, AustriaRecruiting
KU LeuvenLeuven, BelgiumRecruiting
Sozialstiftung Bamberg - Klinikum am BruderwaldBamberg, GermanyWithdrawn
Universitätsklinikum BonnBonn, GermanyRecruiting
Universitätsklinikum KölnCologne, GermanyRecruiting
LVR-Hospital EssenEssen, GermanyRecruiting
Universitätsklinikum FrankfurtFrankfurt, GermanyRecruiting
Universitätsklinikum FreiburgFreiburg im Breisgau, GermanyCompleted
Universitätsmedizin GöttingenGöttingen, GermanyWithdrawn
Medizinische Hochschule HannoverHanover, GermanyWithdrawn
Universitätsklinikum JenaJena, GermanyCompleted
Universitätsklinik LeipzigLeipzig, GermanyRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03320304