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Study identifier: NCT05583747 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

E-field Guided iTBS for Treatment Resistant Depression

Condition: Major Depressive Disorder  ·  Sponsor: Centre for Addiction and Mental Health

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The purpose of this study is to establish how personalization of repetitive transcranial magnetic stimulation (rTMS) can change markers of brain activity and improve treatment response. To do this, all participants will receive the same active form of treatments, but some of the participants in this study will receive intermittent theta burst stimulation (iTBS) rTMS treatment with standard forms of targeting and intensity, and others will receive iTBS rTMS treatment using personalized magnetic resonance imaging (MRI) and electric field (E-field) modeling measures.

This description comes directly from the study's public registry record.

Talk to the study team

Daphne Voineskos, MD  ·  416-535-8501  ·  daphne.voineskos@camh.ca

Always discuss trial participation with your own doctor first.

Locations (2)

Poul Hansen Family Centre for Depression, Toronto Western HospitalToronto, Ontario, CanadaRecruiting
Centre for Addiction and Mental HealthToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05583747