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Condition: De Escalation Therapy Synced from ClinicalTrials.gov · August 07, 2026

Recruiting studies: De Escalation Therapy

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Efficacy of Nab-PHP Versus TCbHP in Neoadjuvant Therapy for HER2-positive Early Breast Cancer
Phase 3 · 1 location(s) · Henan Cancer Hospital · NCT07057427
De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative Colitis
Phase 4 · 1 location(s) · McGill University Health Centre/Research Institute of the Mc · NCT07303686
Early De-escalation of Empirical Antibiotics Treatment for Neutropenic Fever
NA · 1 location(s) · Shanghai Jiao Tong University School of Medicine · NCT04270786
Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy
Phase 3 · 1 location(s) · Sun Yat-sen University · NCT06092957
Step-down Therapy After Long-term Osteoporosis Treatment
Phase 4 · 1 location(s) · National Taiwan University Hospital · NCT07281586
Skipping Hormone Therapy in Low-Risk Early Breast Cancer
Phase 2 · 41 location(s) · UNICANCER · NCT07661927
Evaluating the De-Escalation of Surveillance for Patients Who Have Undergone Curative Treatment for Primary Breast Cance
NA · 1 location(s) · Royal College of Surgeons, Ireland · NCT07616258
Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests.
Phase 2 · 1 location(s) · UNICANCER · NCT06450314
Subcutaneous Interval Lengthening of Vedolizumab for Economic Research
Phase 4 · 1 location(s) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC · NCT06584162
Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic
Phase 3 · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT05577988
A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05491512
Deescalation of Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk
Phase 2 · 2 location(s) · UNICANCER · NCT05297617
Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI
Phase 4 · 1 location(s) · University of Florida · NCT05681702
Reduced-dose vs Standard-dose Irradiation for Low-risk Clinical Target Volume in Nasopharyngeal Carcinoma.
Phase 3 · 6 location(s) · Sun Yat-sen University · NCT07201337
Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit
Phase 3 · 30 location(s) · Assistance Publique - Hôpitaux de Paris · NCT05696093
Ticagrelor De-escalation Strategy in AMI Patients
Phase 4 · 1 location(s) · Dong-A University · NCT04755387
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Eq
Phase 3 · 832 location(s) · NRG Oncology · NCT04852887
THERApy De-escalation for TESTicular Cancer
Phase N/A · 1 location(s) · Queen Mary University of London · NCT06309745
A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsin
Phase 3 · 1 location(s) · University Hospital, Montpellier · NCT07189325
Primary RPLND Versus Systemic Chemotherapy in Good-prognosis Metastatic Testicular Cancer
NA · 1 location(s) · Sahlgrenska University Hospital · NCT07498959
Pilot Randomized Study for Treatment Volume De-Escalation for Spinal Metastases With Stereotactic Body Radiation Therapy
NA · 1 location(s) · IRCCS Sacro Cuore Don Calabria di Negrar · NCT07538024
Four Cycles Taxane With Trastuzumab and Pertuzumab Neoadjuvant Therapy Among Low Risk HER2 Positive Patients
Phase N/A · 1 location(s) · Shu Wang · NCT06722599
Evaluating the De-Escalation of Surveillance for Patients Who Have Undergone Curative Treatment for Breast Cancer
Phase N/A · 1 location(s) · Royal College of Surgeons, Ireland · NCT07572370
ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer
Phase 2 · 1 location(s) · Peking University People's Hospital · NCT06970912
De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)
NA · 1 location(s) · Royal North Shore Hospital · NCT06307015
A Study of Lower Dose Radiation Therapy for People With Prostate Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT07635238
MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC
Phase 2 · 2 location(s) · Tel-Aviv Sourasky Medical Center · NCT07327021
PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer
Phase 2 · 1 location(s) · University of Nebraska · NCT07234981
ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer
Phase 2 · 1 location(s) · University of Miami · NCT06902272
Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer
Phase 2 · 3 location(s) · Olgun Elicin · NCT07058805
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