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Study identifier: NCT05491512 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Condition: HPV · Throat Cancer · Oropharyngeal Carcinoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 2
Planned participants121
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find out if lower doses of radiation may help reduce the side effects of radiation therapy in combination with standard-of-care chemotherapy in people with HPV-positive throat cancer. The chemotherapy drugs used in this study include cisplatin, carboplatin, and 5-fluorouracil (5- FU), paclitaxel and abraxane- (Albumin-bound Paclitaxel).

This description comes directly from the study's public registry record.

Talk to the study team

Nancy Lee, MD  ·  212-639-3341  ·  leen2@MSKCC.ORG

Heiko Schoder, MD  ·  212-639-2079  ·  schoderh@MSKCC.ORG

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering Cancer Center at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer Center at Suffolk-Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05491512