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Study identifier: NCT07058805 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer

Condition: Head and Neck Cancer · Head and Neck Squamous Cell Carcinoma · Oral Cavity Squamous Cell Carcinoma  ·  Sponsor: Olgun Elicin

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

COMPORT is a multicenter phase II clinical trial evaluating a personalized approach to postoperative radiotherapy in patients with head and neck squamous cell carcinoma (HNSCC). The study investigates whether a risk-adapted, compartmentalized radiotherapy strategy can safely reduce the treatment volume, and thus the side effects, without increasing the risk of tumor recurrence. Eligible patients are those with surgically treated cancers of the oral cavity, oropharynx, larynx, or hypopharynx who have a standard indication for postoperative radiotherapy. The primary outcome is the rate of recurrence in anatomical compartments that would normally be irradiated but are intentionally omitted in this study. COMPORT aims to generate high-level evidence to support a more personalized and less toxic standard of care in postoperative head and neck cancer management.

This description comes directly from the study's public registry record.

Talk to the study team

Olgun Elicin, Prof. Dr. med.  ·  +41 31 632 26 32  ·  Olgun.Elicin@insel.ch

Daniel H Schanne, Dr. med.  ·  +41 31 632 26 32  ·  daniel.schanne@insel.ch

Always discuss trial participation with your own doctor first.

Locations (3)

University Hospital of BaselBasel, SwitzerlandRecruiting
Inselspital, Bern University HospitalBern, SwitzerlandRecruiting
University Hospital of ZurichZurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT07058805