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Condition: Recurrent High Grade Gliomas Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Recurrent High Grade Gliomas

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Phase 1 · 1 location(s) · Beijing Biotech · NCT07480941[177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma
EARLY_Phase 1 · 2 location(s) · Beijing Tiantan Hospital · NCT07655869A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refra
EARLY_Phase 1 · 1 location(s) · Children's National Research Institute · NCT07017816MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas
Phase 1/Phase 2 · 3 location(s) · Ann & Robert H Lurie Children's Hospital of Chicago · NCT06712875Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma
Phase 1/Phase 2 · 1 location(s) · Emory University · NCT04590664Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Phase 1 · 1 location(s) · Henry Ford Health System · NCT05686798Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
Phase 1 · 1 location(s) · Plus Therapeutics · NCT05460507ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma
Phase 1 · 1 location(s) · Mayo Clinic · NCT05917145Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.
Phase 1 · 4 location(s) · Tcelltech Inc. · NCT06482905Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progress
Phase 1 · 1 location(s) · City of Hope Medical Center · NCT06815029Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
Phase 1 · 1 location(s) · Ohio State University Comprehensive Cancer Center · NCT06964737PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
Phase 2 · 13 location(s) · Nationwide Children's Hospital · NCT05096481Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma
Phase 2 · 1 location(s) · Mayo Clinic · NCT05465954Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Phase 1 · 17 location(s) · University of California, San Francisco · NCT04485559Study of Letrozole in Recurrent Gliomas
EARLY_Phase 1 · 1 location(s) · University of Cincinnati · NCT03122197Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma
Phase 3 · 1 location(s) · The Third Affiliated hospital of Zhejiang Chinese Medical Un · NCT06330337A Phase I Clinical Study of Intratumoral Injection GC001 in Patient With Recurrent or Progressive Gliomas
Phase 1 · 1 location(s) · GONGCHU Biotechnology Co., Ltd · NCT06660056ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
Phase 2 · 20 location(s) · Nationwide Children's Hospital · NCT06838676A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma
Phase 1 · 1 location(s) · University of Nebraska · NCT05698524DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma o
Phase 2 · 1 location(s) · Ashish Shah · NCT06264388GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma an
Phase 2 · 1 location(s) · Mayo Clinic · NCT07301268Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection
Phase 1/Phase 2 · 1 location(s) · Dushu Lake Hospital Affiliated to Soochow University · NCT06018363Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Phase 1/Phase 2 · 1 location(s) · Essen Biotech · NCT07410494Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors
Phase 2 · 2 location(s) · Clinica Universidad de Navarra, Universidad de Navarra · NCT07424092Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)
NA · 1 location(s) · Northwell Health · NCT05979064Recurrent High Grade Glioma Treated by LITT
NA · 9 location(s) · Beijing Tiantan Hospital · NCT06161610Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)
Phase 1/Phase 2 · 3 location(s) · Plus Therapeutics · NCT01906385A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Gliobl
Phase 1 · 2 location(s) · University of Florida · NCT04573140A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participant
EARLY_Phase 1 · 2 location(s) · St. Joseph's Hospital and Medical Center, Phoenix · NCT06072586MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma
Phase 1 · 1 location(s) · M.D. Anderson Cancer Center · NCT03896568
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.