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Study identifier: NCT05686798 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Condition: Malignant Glioma of Brain · Astrocytoma · Malignant Astrocytoma  ·  Sponsor: Henry Ford Health System

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary goal of this Phase I study is to determine the maximum tolerated dose of oncolytic adenovirus mediated double suicide-gene therapy in combination with fractionated stereotactic radiosurgery in patients with recurrent high-grade astrocytoma undergoing resection.

This description comes directly from the study's public registry record.

Talk to the study team

Tobias Walbert, MD, PhD  ·  3139162723  ·  twalber1@hfhs.org

Nyati Shyam, PhD  ·  734-272-1751  ·  snyati1@hfhs.org

Always discuss trial participation with your own doctor first.

Locations (1)

Henry Ford Health SystemDetroit, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05686798