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Study identifier: NCT07410494 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Condition: Cancer · Breast Cancer · Non-Small Cell Lung Cancer (NSCLC)  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants85
Who can joinAll sexes, 8 Years to 85 Years
Healthy volunteersNo

About this study

This Phase 1/2 study evaluates the safety, feasibility, and preliminary anti-tumor activity of allogeneic donor-derived CAR-NK cells in participants with advanced solid tumors. The CAR target antigen is selected for each participant after tumor profiling using a tissue biopsy and/or liquid biopsy. Participants will receive either a single-target or dual-target CAR-NK product based on the antigen profile.

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, PHD  ·  +12077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07410494