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Study identifier: NCT03896568 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Condition: IDH1 wt Allele · Recurrent Anaplastic Astrocytoma · Recurrent Glioblastoma  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 1
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back (recurrent). Oncolytic adenovirus DNX-2401 is made from the common cold virus that has been changed in the laboratory to make it less likely to cause an infection (such as a cold). The virus is also changed to target brain cancer cells and attack them.

This description comes directly from the study's public registry record.

Talk to the study team

Frederick Lang  ·  713-792-2400  ·  flang@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03896568