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Study identifier: NCT06264388 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Condition: High Grade Glioma · Anaplastic Astrocytoma  ·  Sponsor: Ashish Shah

PhasePhase 2
Planned participants33
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to determine if the investigational products, DB107-RRV and DB107-FC, as a combination treatment will shrink high-grade glioma (HGG) in patients with recurrent/progressive, resectable or unresectable disease and increase the time that disease is controlled.

This description comes directly from the study's public registry record.

Talk to the study team

Leonela Wright, MSN, RN  ·  305-243-0864  ·  lxw612@med.miami.edu

Ashish Shah, MD  ·  3052436946  ·  ashah@med.miami.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Miami HospitalMiami, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06264388