Recruiting studies: Total Neoadjuvant Therapy

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT07448142 A Study of Tucatinib and Trastuzumab in People With Rectal Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05672524 ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer
Phase N/A · 1 location(s) · Gene Solutions · NCT06589388 Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II
Phase 2 · 1 location(s) · Ain Shams University · NCT07095439 Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy
NA · 1 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT03587480 Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue
Phase 2 · 8 location(s) · Swiss Cancer Institute · NCT06835049 Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab a
Phase 2 · 1 location(s) · Dechang Diao · NCT07005570 Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer
Phase 2 · 4 location(s) · Virginia Commonwealth University · NCT04643366 Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer
Phase 2 · 1 location(s) · Jinhua Central Hospital · NCT06204094 A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer
Phase 2 · 1 location(s) · First Affiliated Hospital of Wenzhou Medical University · NCT07347951 Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric Junction
Phase 2 · 10 location(s) · Erasmus Medical Center · NCT06161818 A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer
Phase 2 · 2 location(s) · Osaka University · NCT05939661 Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)
Phase 3 · 1 location(s) · Peking University Cancer Hospital & Institute · NCT06229041 Hyperthermia With Chemoradiotherapy in Rectal Cancer
NA · 2 location(s) · University Hospital Tuebingen · NCT06831981 Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
Phase 2 · 1 location(s) · AC Camargo Cancer Center · NCT06793137 Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer
Phase 2/Phase 3 · 2 location(s) · Ukrainian Society of Clinical Oncology · NCT06028737 A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Ne
Phase 3 · 1 location(s) · Tao Zhang · NCT07113275 SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer
Phase 1 · 1 location(s) · University of Miami · NCT05412082 ADAR1 Expression Level in Rectal Cancer
Phase N/A · 1 location(s) · Necmettin Erbakan University · NCT07108348 Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer Patients
Phase 2 · 1 location(s) · Menoufia University · NCT06812728 Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT)
Phase 2 · 1 location(s) · Shandong Cancer Hospital and Institute · NCT07026422 Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.
Phase 2 · 2 location(s) · brenner baruch · NCT06940388 Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001
Phase 2 · 3 location(s) · University of Nebraska · NCT05254327 Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Assoc
Phase N/A · 1 location(s) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05984576 Hyperpolarized 13C-MRI and Radiomics in Rectal Cancer
Phase N/A · 1 location(s) · Chang Gung Memorial Hospital · NCT07730541 Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy
Phase 1/Phase 2 · 1 location(s) · Fudan University · NCT07561060 Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma
Phase 2 · 1 location(s) · National Taiwan University Hospital · NCT06764355 Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study
Phase 3 · 1 location(s) · West China Hospital · NCT07020247 A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05851924 SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC
NA · 1 location(s) · Union Hospital, Tongji Medical College, Huazhong University · NCT07474103

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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.