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Study identifier: NCT06229041 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)

Condition: Rectal Cancer  ·  Sponsor: Peking University Cancer Hospital & Institute

PhasePhase 3
Planned participants472
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare the PCR rate between Total Neoadjuvant Treatment ±Immunotherapy in high risk locally advanced rectal cancer. The main questions it aims to answer are: * The PCR rate between the two groups * The 3years DFS between the two groups * Chemoradiotherapy and immunotherapy toxicity * Postoperative complications Participants will receive total neoadjuvant treatment ±immunotherapy followed by surgery. Researchers will compare neoadjuvant treatment ±immunotherapy to see the PCR rate.

This description comes directly from the study's public registry record.

Talk to the study team

WU AI WEN, M.D.  ·  +8613911577190  ·  wuaw@sina.com

DONG QIU SHI  ·  +8618600172425  ·  dongqiushi1024@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Cancer HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06229041