Condition: Gastric Cancer · Stomach Cancer · GastroEsophageal Cancer · Sponsor: Ukrainian Society of Clinical Oncology
The main goal of this study is to investigate the proportion of participants with locally advanced gastric and gastroesophageal adenocarcinoma without previous treatment during the last 5 years who can tolerate all planned cycles of chemotherapy and radical surgical treatment who will be prospectively randomized into two groups to undergo one of two chemotherapy regimens, followed by surgery: 1. 8 cycles of Total Neoadjuvant ChemoTherapy (TNT) with 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin, and Docetaxel (FLOT) followed by surgery. 2. 4 cycles of Neoadjuvant FLOT chemotherapy scheme preoperatively and 4 adjuvant FLOT cycles postoperatively.
This description comes directly from the study's public registry record.
Mykyta Pepenin, MD · +380959448858 · pepenin95@gmail.com
Oleksii Dobrzhanksiy, MD · +380638760185 · alekseydobrzhanskiy@gmail.com
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| National Cancer Institute | Vilnius, Lithuania | Recruiting |
| National Cancer Institute | Kyiv, Ukraine | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06028737