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Study identifier: NCT07561060 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy

Condition: Rectal Cancer  ·  Sponsor: Fudan University

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an open-label, multi-center, single-arm clinical study. All patients received 4-6 cycles total neoadjuvant therapy plus concurrent tislelizumab immunotherapy, then underwent clinical response assessment. Patients who achieved CR (cCR+ pCR confirmed by local resection of ncCR) continue tislelizumab combined with CAPOX for another 4 cycles and tislelizumab for 9 cycles, then Watch and Wait. Patients who did not achieved CR underwent total mesorectal excision (TME).

This description comes directly from the study's public registry record.

Talk to the study team

Jianmin Xu, MD  ·  +862164041990  ·  xujmin@aliyun.com

Wenju Chang, MD  ·  13764476150  ·  chang_erich@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Zhongshan Hospital, ShanghaiShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07561060