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Study identifier: NCT07005570 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer (SPARK)

Condition: pMMR/MSS Locally Advanced Rectal Cancer  ·  Sponsor: Dechang Diao

PhasePhase 2
Planned participants86
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Safety and efficacy of Short-Course Radiotherapy Followed by Sequential Chemotherapy with or without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer. Complete Response (CR) Rate of Short-Course Radiotherapy Followed by Sequential Chemotherapy with or without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Dechang Diao, Dr  ·  13416119782  ·  diaodch3@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sixth Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07005570