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Study identifier: NCT03587480 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy

Condition: Rectal Neoplasm Malignant  ·  Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

PhaseNA
Planned participants250
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Treatment for Low rectal cancer, especially in patients with regional lymph node metastasis are quite different between Japanese guideline (JSCCR) and western countries' guideline (NCCN, ESMO). While Japanese scholars advocate total mesorectal excision (TME) plus lateral lymph node dissection (LLND), European and American scholars advocate TME alone after Neoadjuvant Chemo-radiotherapy (nCRT), without the need of LLND. Accordingly, this clinical trial is designed to directly compare the efficacy and safety of these two treatment strategies for low rectal cancer with regional lymph node metastasis. It will provide high-level clinical evidence for the treatment of low rectal cancer with suspected local lymph node metastasis

This description comes directly from the study's public registry record.

Talk to the study team

Yanxin Luo  ·  020-38250745  ·  luoyx25@mail.sysu.edu.cn

Shaoyong Peng  ·  86-13435613566  ·  pengshy9@mail2.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Sixth Affiliate Hospital of Sun Yat-Sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT03587480