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Condition: Rectal Neoplasm Malignant Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Rectal Neoplasm Malignant

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Pa
Phase 3 · 60 location(s) · ECOG-ACRIN Cancer Research Group · NCT05863195
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Phase 1 · 40 location(s) · TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) · NCT06625775
Resilience and Equity in Aging, Cancer, and Health (REACH)
NA · 1 location(s) · Dana-Farber Cancer Institute · NCT04674267
Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Base
Phase N/A · 4 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT05523245
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Phase N/A · 1 location(s) · University of Missouri-Columbia · NCT02838836
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Phase 1 · 7 location(s) · Akamis Bio · NCT06459869
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Phase 1/Phase 2 · 27 location(s) · Institut de Recherches Internationales Servier · NCT05786924
Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT07448142
PARLAR-02 Trial:Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage
NA · 1 location(s) · Third Military Medical University · NCT07036588
A Study of Tucatinib and Trastuzumab in People With Rectal Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05672524
Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer
Phase 2 · 1 location(s) · Fudan University · NCT06455124
ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer
Phase N/A · 1 location(s) · Gene Solutions · NCT06589388
TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
Phase 4 · 1 location(s) · Nova Scotia Health Authority · NCT05148494
Preoperative Radiotherapy And ASTX660 in Rectum Cancer
Phase 1 · 2 location(s) · Gustave Roussy, Cancer Campus, Grand Paris · NCT05912075
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer
Phase 1 · 1 location(s) · Jonsson Comprehensive Cancer Center · NCT04703101
Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II
Phase 2 · 1 location(s) · Ain Shams University · NCT07095439
Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastati
Phase 1 · 22 location(s) · National Cancer Institute (NCI) · NCT05803382
MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer
Phase 1 · 1 location(s) · Medical College of Wisconsin · NCT04808323
Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
Phase N/A · 1 location(s) · Amsterdam UMC, location VUmc · NCT07056374
A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Construct
Phase N/A · 1 location(s) · Samsung Medical Center · NCT05566249
Developing and Testing the Effect of Online Interactive Videos in Improving Low Anterior Resection Syndrome.
NA · 1 location(s) · Chang Gung Memorial Hospital · NCT06628674
Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer
Phase N/A · 1 location(s) · Helse Stavanger HF · NCT01762813
The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer
Phase 2 · 1 location(s) · Fudan University · NCT05628038
Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer
NA · 1 location(s) · Second Affiliated Hospital, School of Medicine, Zhejiang Uni · NCT07359989
SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Ca
Phase 2 · 1 location(s) · First Affiliated Hospital of Zhejiang University · NCT06864013
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy
NA · 1 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT03587480
Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision
NA · 1 location(s) · Daping Hospital and the Research Institute of Surgery of the · NCT06633133
Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC
Phase 2 · 2 location(s) · Prakash Pandalai · NCT04779554
A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally
Phase 2/Phase 3 · 2 location(s) · Suzhou Suncadia Biopharmaceuticals Co., Ltd. · NCT07454720
Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab a
Phase 2 · 1 location(s) · Dechang Diao · NCT07005570
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.