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Study identifier: NCT05523245 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI

Condition: Rectal Cancer  ·  Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

PhaseN/A
Planned participants1700
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Establish a deep learning model based on multi-parameter magnetic resonance imaging to predict the efficacy of neoadjuvant therapy for locally advanced rectal cancer.This study intends to combine DCE with conventional MRI images for DL, establish a multi-parameter MRI model for predicting the efficacy of CRT, and compare it with the DL and non-artificial quantitative MRI diagnostic model constructed by conventional MRI to evaluate the role of DL in MRI predicting CRT. And this study also tries to build a DL platform to assess the efficacy of LARC neoadjuvant radiotherapy and chemotherapy, accurately assess patients' complete respose (pCR) after CRT, and provide an important basis for guiding clinical decision-making.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaochun Meng  ·  13719166488  ·  mengxch3@mail.sysu.edu.cn

Peiyi Xie  ·  13724071514  ·  xiepy6@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (4)

Sixth Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Jinan UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
Fifth Affiliated Hospital, Sun Yat-sen UniversityZhuhai, Guangdong, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05523245