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Study identifier: NCT06459869 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

Condition: Locally Advanced Rectal Cancer (LARC)  ·  Sponsor: Akamis Bio

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The FORTRESS trial (NG-350A-03) is an open-label, single-arm, and multicentre trial of NG-350A in combination with chemoradiotherapy (CRT) in adult patients with locally advanced rectal cancer (LARC) and at least one risk factor for local or distant recurrence.

This description comes directly from the study's public registry record.

Talk to the study team

Vice President Head of Clinical Operations  ·  +1 (484) 362-8918  ·  robert.maietta@akamisbio.com

https://www.FortressStudy.org  ·  oliver.rosen@akamisbio.com

Always discuss trial participation with your own doctor first.

Locations (7)

University of Southern CaliforniaLos Angeles, California, United StatesActive Not Recruiting
AdventHealth OrlandoOrlando, Florida, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
University College London NHS FTLondon, United KingdomRecruiting
The Royal Marsden NHS Foundation TrustSutton, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06459869