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Condition: Locally Advanced Rectal Cancer Larc Synced from ClinicalTrials.gov · July 29, 2026

Recruiting studies: Locally Advanced Rectal Cancer Larc

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Phase 1 · 7 location(s) · Akamis Bio · NCT06459869SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Ca
Phase 2 · 1 location(s) · First Affiliated Hospital of Zhejiang University · NCT06864013Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression
Phase 2 · 1 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT07176182A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer
Phase 2 · 1 location(s) · First Affiliated Hospital of Wenzhou Medical University · NCT07347951Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC
Phase 2 · 3 location(s) · Union Hospital, Tongji Medical College, Huazhong University · NCT06542588Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer
Phase 2 · 8 location(s) · Beijing Friendship Hospital · NCT05245474Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.
Phase 2 · 2 location(s) · brenner baruch · NCT06940388Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC
Phase 2 · 1 location(s) · The First Affiliated Hospital with Nanjing Medical Universit · NCT07646639Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant The
Phase N/A · 1 location(s) · Beijing Friendship Hospital · NCT07393048Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Phase 2 · 1 location(s) · Union Hospital, Tongji Medical College, Huazhong University · NCT06802666Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
Phase 2 · 2 location(s) · Cancer Institute and Hospital, Chinese Academy of Medical Sc · NCT07040098Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study
Phase 3 · 1 location(s) · West China Hospital · NCT07020247SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC
NA · 1 location(s) · Union Hospital, Tongji Medical College, Huazhong University · NCT07474103SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC
Phase 2 · 1 location(s) · Ruijin Hospital · NCT07198165Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer
NA · 1 location(s) · Peking Union Medical College Hospital · NCT06653452Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIF
Phase 2 · 1 location(s) · Sixth Affiliated Hospital, Sun Yat-sen University · NCT06923345Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rec
NA · 1 location(s) · Centre Hospitalier Universitaire Saint Pierre · NCT06761287Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advance
NA · 1 location(s) · University of South Florida · NCT06380101SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC
Phase 2 · 1 location(s) · Shandong Provincial Hospital · NCT07284992Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC
Phase 2 · 1 location(s) · Sun Yat-sen University · NCT06911684Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer
Phase N/A · 2 location(s) · National Cancer Institute, Naples · NCT07269249The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surger
Phase 3 · 6 location(s) · Sun Yat-sen University · NCT05984485SCRT Followed by Camrelizumab Combined With Fluzoparib and Chemotherapy as Neoadjuvant Therapy for LARC
Phase 2 · 1 location(s) · Huazhong University of Science and Technology · NCT06516445
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.