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Study identifier: NCT06542588 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC

Condition: Rectal Cancer  ·  Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

PhasePhase 2
Planned participants29
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The study is a multicenter, open-label, phase II clinical study, and the purpose of the study is to explore the complete response rate (CR, Defined as pathological complete response (pCR) + Clinical complete response (cCR)) of patients with RAS/BRAF wild type locally advanced rectal cancer(LARC) treated with short-term radiotherapy, sequential HLX07, Serplulimab and CAPOX. A total of 29 patients were included in this study.

This description comes directly from the study's public registry record.

Talk to the study team

zhenyu Lin, MD  ·  027-85871982  ·  whxhlzy@hust.edu.cn

Tao Zhang, MD

Always discuss trial participation with your own doctor first.

Locations (3)

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyHubei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06542588