Condition: Locally Advanced Rectal Carcinoma · Rectal Adenocarcinoma · Stage II Rectal Cancer AJCC v8 · Sponsor: Jonsson Comprehensive Cancer Center
This phase I trial investigates how well short-course radiation therapy followed by combination chemotherapy works in treating patients with stage II-III rectal cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Chemotherapy drugs, such as leucovorin, fluorouracil, oxaliplatin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving short-course radiation therapy and combination chemotherapy may reduce the need for surgery and therefore improve quality of life.
This description comes directly from the study's public registry record.
Vincent Basehart · 310 267-8954 · vbasehart@mednet.ucla.edu
Always discuss trial participation with your own doctor first.
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04703101