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Condition: Cutaneous Squamous Cell Cancer Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Cutaneous Squamous Cell Cancer

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Personalised Immunotherapy Platform
Phase N/A · 3 location(s) · Melanoma Institute Australia · NCT06536257Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patient
Phase 2 · 153 location(s) · NRG Oncology · NCT06532279A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcino
EARLY_Phase 1 · 2 location(s) · Dana-Farber Cancer Institute · NCT06664151BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or S
Phase 2 · 225 location(s) · National Cancer Institute (NCI) · NCT05136196Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised Patients
NA · 11 location(s) · Alpha Tau Medical LTD. · NCT06615635Next-gen Flow Cytometry to Find Immune Profiles, Treatment Response, and Toxicity Markers in Skin Cancer Patients Treate
Phase N/A · 1 location(s) · Instituto de Investigación Biomédica de Salamanca · NCT07064330A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers
Phase 1/Phase 2 · 20 location(s) · Hummingbird Bioscience · NCT05910827A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients
EARLY_Phase 1 · 2 location(s) · Marissa Lobl · NCT07286318A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial
Phase 1 · 12 location(s) · EvolveImmune United, Inc · NCT07217171A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malign
Phase 1/Phase 2 · 13 location(s) · GV20 Therapeutics · NCT05669430Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck
NA · 1 location(s) · Indiana University · NCT05108090Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC
Phase 1 · 1 location(s) · City of Hope Medical Center · NCT05085496Neoadjuvant Pembrolizumab in Cutaneous Squamous Cell Carcinoma
Phase 2 · 3 location(s) · Queensland Health · NCT05025813MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer
Phase 2 · 1 location(s) · University of Vermont Medical Center · NCT06998342Study of a Strategy Integrating Adjuvant Radiation Therapy Versus Strategy Based on Monitoring in the Treatment of Carci
Phase 3 · 28 location(s) · Centre Leon Berard · NCT06692556Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.
NA · 1 location(s) · Alpha Tau Medical LTD. · NCT03889899Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)
Phase 1/Phase 2 · 1 location(s) · Falo, Louis, MD · NCT05377905Towards Cure Via Only Ultra-short ICB in CSCC
Phase 2 · 5 location(s) · The Netherlands Cancer Institute · NCT06823479A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Phase 1 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05859074Cutaneous Squamous Cell Carcinoma Staging Study
Phase N/A · 2 location(s) · Queen Mary University of London · NCT05695222Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carci
Phase 2 · 1 location(s) · University of Michigan Rogel Cancer Center · NCT06580054Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk
Phase 2 · 1 location(s) · University of California, Davis · NCT06990737ctDNA in Cutaneous Squamous Cell Carcinoma
Phase N/A · 1 location(s) · Massachusetts Eye and Ear Infirmary · NCT06875609L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma
Phase 2 · 19 location(s) · Philogen S.p.A. · NCT07228442A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Phase 1 · 158 location(s) · Seagen, a wholly owned subsidiary of Pfizer · NCT04389632Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune Syst
Phase 2 · 38 location(s) · National Cancer Institute (NCI) · NCT07042295Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metasta
Phase 1/Phase 2 · 26 location(s) · National Cancer Institute (NCI) · NCT05896839Usefulness of Post-Operative Radiotherapy in High-grade Cutaneous Squamous Cell Carcinoma: an Observational Study
Phase N/A · 1 location(s) · Fondazione IRCCS Policlinico San Matteo di Pavia · NCT06879964Outcome Research of a European Registry Platform on Real-world Treatment Data of Patients with Advanced NMSC
Phase N/A · 1 location(s) · EuMelaReg gGmbH · NCT05741073MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
Phase 1 · 2 location(s) · Memgen, Inc. · NCT05076760
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.