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Study identifier: NCT05669430 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

Condition: Solid Tumor, Adult · Refractory Cancer · Endometrial Carcinoma (EC)  ·  Sponsor: GV20 Therapeutics

PhasePhase 1/Phase 2
Planned participants365
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

This description comes directly from the study's public registry record.

Talk to the study team

GV20 Therapeutics  ·  617-256-2846  ·  clinicaltrials@gv20tx.com

Always discuss trial participation with your own doctor first.

Locations (13)

The Angeles Clinic and Research InstituteLos Angeles, California, United StatesRecruiting
HealthONE Clinic Services Oncology - Hematology, LLC d/b/a Sarah Cannon Research Institute at HealthONEDenver, Colorado, United StatesNot Yet Recruiting
Yale UniversityNew Haven, Connecticut, United StatesRecruiting
Florida Cancer Specialists & Research Institute, LLCFort Myers, Florida, United StatesNot Yet Recruiting
Community Health Network, Inc.Indianapolis, Indiana, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Barbara Ann Karmanos Cancer Hospital dba Karmanos Cancer CenterDetroit, Michigan, United StatesRecruiting
NYU Langone HealthNew York, New York, United StatesRecruiting
Oregon Health & Science UniversityPortland, Oregon, United StatesRecruiting
Verdi Oncology Tennessee, Scri Oncology PartnersNashville, Tennessee, United StatesNot Yet Recruiting
Oncology Consultants, P.A.Houston, Texas, United StatesRecruiting
The University of Texas M. D. Anderson Cancer CenterHouston, Texas, United StatesRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05669430