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Study identifier: NCT06692556 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of a Strategy Integrating Adjuvant Radiation Therapy Versus Strategy Based on Monitoring in the Treatment of Carcinomas Spinocellular With High Risk of Recurrence

Condition: Cutaneous Squamous Cell Carcinoma (CSCC)  ·  Sponsor: Centre Leon Berard

PhasePhase 3
Planned participants266
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate a strategy integrating adjuvant radiation therapy versus strategy based on monitoring in the treatment of carcinomas spinocellular with high risk of recurrence (SCC). The investigators will compare the disease-free survival (DFS) of patients treated with adjuvant radiation therapy versus surveillance in high risk of recurrence SCC. The main question it aims to answer is: Is DFS different between the "adjuvant radiotherapy" group and the "surveillance" group? Participants will: * be distributed in one of the two arms * will be followed up every 4 months for 2 years, then every 6 months (clinical examination, identification of concomitant treatments, imaging, quality-of-life questionnaire) * followed up until their death or their progression whether local, regional or metastatic

This description comes directly from the study's public registry record.

Talk to the study team

Julien GAUTIER  ·  +33 4.26.55.68.29  ·  julien.gautier@lyon.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (28)

Centre Hospitalier Emile RouxLe Puy-en-Velay, Auvergne-Rhône-Alpes, FranceWithdrawn
Hospices Civils de Lyon - Centre Hospitalier Lyon SudPierre-Bénite, Auvergne-Rhône-Alpes, FranceNot Yet Recruiting
Centre Georges François LeclercDijon, Bourgogne-Franche-Comté, FranceActive Not Recruiting
Centre Hospitalier Romans - Hopitaux Drôme NordRomans-sur-Isère, Drôme, FranceRecruiting
Centre de Radiothérapie Marie CurieValence, Drôme, FranceNot Yet Recruiting
Centre Hospitalier de ValenceValence, Drôme, FranceRecruiting
Centre Hospitalier Régional Universitaire de Brest - Hôpital MorvanBrest, Finistère, FranceWithdrawn
Hôpital de la Cavale BlancheBrest, Finistère, FranceNot Yet Recruiting
Centre Hospitalier Universitaire de BordeauxPessac, Gironde, FranceActive Not Recruiting
Centre Hospitalier Annecy GenevoisMetz-Tessy, Haute-Savoie, FranceRecruiting
Centre Hospitalier Universitaire de RennesRennes, Ille-et-Vilaine, FranceNot Yet Recruiting
Centre Hospitalier Universitaire de Grenoble-AlpesLa Tronche, Isère, FranceNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06692556