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Study identifier: NCT05377905 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)

Condition: Cutaneous Squamous Cell Carcinoma · Skin Cancers - Squamous Cell Carcinoma  ·  Sponsor: Falo, Louis, MD

PhasePhase 1/Phase 2
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to test a new method of experimental treatment for cutaneous squamous cell skin cancer, using small adhesive-like patches (a micro-needle applicator or MNA for short), which have dozens of very small micro-needles loaded with extremely low doses of doxorubicin, a chemotherapy agent. The overall goal of this study is to test the safety and effectiveness of these patches. The investigators have established the highest tolerated dose at 50 micrograms in a previous study for a different type of cancer that affects the skin. The investigators will thoroughly evaluate the skin where the patches are applied.

This description comes directly from the study's public registry record.

Talk to the study team

Charity L Ruhl, LPN  ·  1-412-647-2013  ·  ruhlcl@upmc.edu

Nicolena Verardi  ·  1-412-864-3682  ·  verardin3@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05377905