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Condition: Diffuse Intrinsic Pontine Glioma Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Diffuse Intrinsic Pontine Glioma

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Phase 1 · 1 location(s) · Baylor College of Medicine · NCT04099797Combination Therapy for the Treatment of Diffuse Midline Gliomas
Phase 2 · 32 location(s) · University of California, San Francisco · NCT05009992FUS Etoposide for DMG
Phase 1 · 1 location(s) · Columbia University · NCT05762419Atovaquone Combined With Radiation in Children With Malignant Brain Tumors
Phase 1 · 2 location(s) · Emory University · NCT06624371Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
Phase 1/Phase 2 · 1 location(s) · University of Miami · NCT05956821Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Di
Phase 1 · 20 location(s) · Children's Oncology Group · NCT06894979Study of Olutasidenib and Temozolomide in HGG
Phase 2 · 20 location(s) · Rigel Pharmaceuticals · NCT06161974PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
Phase 2 · 13 location(s) · Nationwide Children's Hospital · NCT05096481Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
Phase 3 · 50 location(s) · Gustave Roussy, Cancer Campus, Grand Paris · NCT05476939rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
Phase 1 · 3 location(s) · Ann & Robert H Lurie Children's Hospital of Chicago · NCT04943848ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
Phase 2 · 20 location(s) · Nationwide Children's Hospital · NCT06838676A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) G
Phase 1/Phase 2 · 127 location(s) · National Cancer Institute (NCI) · NCT05099003Targeted Pediatric High-Grade Glioma Therapy
Phase N/A · 21 location(s) · Nationwide Children's Hospital · NCT05839379Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
Phase 1/Phase 2 · 12 location(s) · Milton S. Hershey Medical Center · NCT06465199Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma
Phase 1 · 1 location(s) · Capital Medical University · NCT05717699H3K27M-specific Immune Effector Cells Targeting DMG/DIPG
Phase 1/Phase 2 · 1 location(s) · Shenzhen Geno-Immune Medical Institute · NCT07501156PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy
Phase 1 · 3 location(s) · University of Florida · NCT04837547CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children a
Phase 1 · 1 location(s) · OX2 Therapeutics · NCT06305910xPedite: A Study to Expedite DIPG and DMG Research
Phase N/A · 1 location(s) · xCures · NCT06140719Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliom
Phase 1 · 1 location(s) · Seattle Children's Hospital · NCT04185038A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma
Phase 2 · 1 location(s) · Tata Memorial Centre · NCT04250064Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma
Phase 1 · 1 location(s) · Capital Medical University · NCT05717712Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG
Phase 1 · 1 location(s) · Chulalongkorn University · NCT06221553Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic
Phase 1 · 1 location(s) · Sun Yat-sen University · NCT07584499GD2-CAR T Cells for Pediatric Brain Tumours
Phase 1 · 1 location(s) · Bambino Gesù Hospital and Research Institute · NCT05298995Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Phase 2 · 20 location(s) · Nationwide Children's Hospital · NCT05843253Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Phase N/A · 1 location(s) · Children's National Research Institute · NCT01106794Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors
Phase 1/Phase 2 · 4 location(s) · Nationwide Children's Hospital · NCT05278208A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
EARLY_Phase 1 · 21 location(s) · Nationwide Children's Hospital · NCT04655404CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma
Phase 1/Phase 2 · 35 location(s) · Children's Oncology Group · NCT04870944
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.