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Study identifier: NCT04250064 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma

Condition: DIPG  ·  Sponsor: Tata Memorial Centre

PhasePhase 2
Planned participants40
Who can joinAll sexes, 3 Years to 18 Years
Healthy volunteersNo

About this study

In this study, the investigators are testing improvement in survival outcomes in DIPG patients when stratified with MR perfusion score and treated with the said protocol. Newly diagnosed DIPG patients will undergo MRI perfusion study in addition to the usual MRI at diagnosis and will be stratified into hyperperfused or hypoperfused tumours. The hyperperfused patients will receive additional low dose Bevacizumab weekly with conventional standard radiotherapy. The hypo-perfused patients will receive ultra-low-dose radiotherapy fractionation equivalent to conventional RT biological dose.

This description comes directly from the study's public registry record.

Talk to the study team

Rahul Krishnatry, Dr  ·  022-24177000  ·  krishnatry@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Tata Memorial HospitalMumbai, Maharashtra, IndiaRecruiting

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Source record: clinicaltrials.gov/study/NCT04250064