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Study identifier: NCT07501156 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

Condition: Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma  ·  Sponsor: Shenzhen Geno-Immune Medical Institute

PhasePhase 1/Phase 2
Planned participants30
Who can joinAll sexes, 2 Years to 70 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the feasibility, safety and efficacy of H3K27M-specific engineered immune effector (EIE) therapy in patients with high-risk, H3K27M-positive diffuse midline glioma/diffuse intrinsic pontine glioma. Another goal of the study is to learn more about the function of the anti-H3K27M EIE cells and their persistency in patients.

This description comes directly from the study's public registry record.

Talk to the study team

Lung-Ji Chang, Ph.D  ·  +86 0755-86573763  ·  c@szgimi.org

Always discuss trial participation with your own doctor first.

Locations (1)

Shenzhen Geno-immune Medical InstituteShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07501156