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Condition: Depressive Episode Major Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Depressive Episode Major

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Phase 3 · 68 location(s) · Intra-Cellular Therapies, Inc. · NCT06372964Reward Processing and Depressive Subtypes: Identifying Neural Biotypes
Phase N/A · 1 location(s) · San Francisco Veterans Affairs Medical Center · NCT06080646Comparing Uni- and Bi-lateral TBS in Major Depression
NA · 1 location(s) · The Royal Ottawa Mental Health Centre · NCT04142996tDCS: Sleep to Mood in Depression (S2M-D)
NA · 1 location(s) · NYU Langone Health · NCT07572526Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway
NA · 1 location(s) · First Affiliated Hospital of Zhejiang University · NCT05913960Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Di
NA · 1 location(s) · University Hospital, Montpellier · NCT07031817Belief Update: The Effects of Depression and Antidepressants in Older People
NA · 2 location(s) · Hospital Center Guillaume Régnier · NCT07681492A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
Phase 3 · 1 location(s) · Korea Otsuka Pharmaceutical Co., Ltd. · NCT03423680Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) and the P
NA · 11 location(s) · Emobot · NCT06601140A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Phase 3 · 180 location(s) · Eli Lilly and Company · NCT07412756Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)
NA · 1 location(s) · NYU Langone Health · NCT07111390M3VAS Validation in Polish Population
Phase N/A · 1 location(s) · Medical University of Gdansk · NCT06412562Personalized Ultrasonic Brain Stimulation for Depression (R61)
Phase 1/Phase 2 · 1 location(s) · Brian Mickey · NCT06902298Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents
NA · 1 location(s) · University of Texas at Austin · NCT06523439Relevance of a Telemedicine Monitoring in the Management of Depression
NA · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT06076317Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Type
Phase 3 · 1 location(s) · University of Sao Paulo · NCT07412132Feasibility and Efficacy of rTMS in Depression in Patients With Autism Spectrum Disorder (ASD)
NA · 1 location(s) · Hospital Center Guillaume Régnier · NCT07258914Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Phase N/A · 1 location(s) · Unity Health Toronto · NCT06732089Presynaptic Imaging in Major Depressive Episodes After COVID-19
Phase N/A · 1 location(s) · Centre for Addiction and Mental Health · NCT06086366Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
NA · 1 location(s) · Andrew Krystal · NCT07127913Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period.
Phase N/A · 2 location(s) · University Hospital, Ghent · NCT05961306Metabolomics During ElectroConvulsivoTherapy
NA · 1 location(s) · Hôpital le Vinatier · NCT05973643ALTO-100 in Bipolar Disorder With Depression (BD-D)
Phase 2 · 27 location(s) · Alto Neuroscience · NCT06656416Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study
Phase N/A · 1 location(s) · Jiangsu Province Nanjing Brain Hospital · NCT07247344Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episod
NA · 7 location(s) · Alcediag · NCT06507787Transition Care for FEP
Phase N/A · 2 location(s) · University of Chicago · NCT07713849Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode
Phase 3 · 9 location(s) · Centre Hospitalier Universitaire de Nīmes · NCT03646058Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression
NA · 1 location(s) · The Royal Ottawa Mental Health Centre · NCT06152705rTMS Response Trajectories in Depression
NA · 1 location(s) · Chinese University of Hong Kong · NCT03348761A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Phase 2 · 25 location(s) · Tonix Pharmaceuticals, Inc. · NCT07621237
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.