Condition: Bipolar Disorder · Major Depressive Disorder · Sponsor: Alcediag
Depression is one of the most common mental disorders, affecting nearly 10% of men and 20% of women worldwide. It is associated with a significant increase in mortality, mainly due to suicidal behavior. The Diagnostic and Statistical Manual of Mental Disorders (DSM) defines a Major Depressive Episode (MDE) by a combination of at least five different symptoms, with at least one depressed mood or loss of interest. MDEs can occur in isolation or as part of Major Depressive Disorder (MDD) or bipolar disorder (BD). Bipolar disorders affect 2% of the world's population and are defined by episodes of mania (Type I BD) or hypomania (Type II BD) alternating with episodes of depression and periods of remission. Depression occurring whether in the context of BD or MDD is defined with the same clinical criteria. However, the pharmacological treatments are different in the two groups. In particular, antidepressants prescribed without a thymoregulator in bipolar patients can lead to a worsening of the episode, favoring suicidal behavior or a manic turn. The average interval between the onset of BD symptoms and appropriate diagnosis is estimated to be approximately 7 years, which delays appropriate management and treatment and increases the risk of suicide. Biological markers able to differentiate between the different types of depression were lacking before the advent of EDIT-B®; one of the main objectives of this research is to measure the clinical impact of the use of EDIT-B® in the s…
This description comes directly from the study's public registry record.
Diana Vetter · +33788970700 · diana.vetter@alcediag-alcen.com
Benjamin Dubuc · benjamin.dubuc@alcediag-alcen.com
Always discuss trial participation with your own doctor first.
| CH Erstein | Erstein, France | Not Yet Recruiting |
| AP-HP Corentin Celton | Issy-les-Moulineaux, France | Not Yet Recruiting |
| Etablissement Public de Santé Mentale (EPSM) 74 | La Roche-sur-Foron, France | Not Yet Recruiting |
| Clinique Villa des Roses | Lyon, France | Recruiting |
| Clinique Le Clos Montaigne | Montrond-les-Bains, France | Recruiting |
| GHU Paris Psychiatrie et Neurosciences | Paris, France | Recruiting |
| Clinique Médicale de Ville d'Avray | Ville-d'Avray, France | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06507787