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Condition: Bipolar I Depression Synced from ClinicalTrials.gov · August 09, 2026

Recruiting studies: Bipolar I Depression

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

NMDA Receptor Modulation for the Treatment of Bipolar I Disorder
Phase 2 · 1 location(s) · China Medical University Hospital · NCT05977023
SYNCED - SYNChronized Eating in Bipolar Depression Study
NA · 1 location(s) · University of Ottawa · NCT06560957
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Phase 3 · 68 location(s) · Intra-Cellular Therapies, Inc. · NCT06372964
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Phase 2 · 1 location(s) · Mclean Hospital · NCT05837104
Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine
Phase 1/Phase 2 · 6 location(s) · Mapi Pharma Ltd. · NCT07185815
Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Type
Phase 3 · 1 location(s) · University of Sao Paulo · NCT07412132
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
NA · 1 location(s) · KU Leuven · NCT07211750
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
Phase 2 · 26 location(s) · LB Pharmaceuticals Inc. · NCT07494305
LHC-CIDI-5 in Hong Kong
Phase N/A · 1 location(s) · The University of Hong Kong · NCT06804525
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I
Phase 2 · 33 location(s) · AbbVie · NCT06696755
ALTO-100 in Bipolar Disorder With Depression (BD-D)
Phase 2 · 27 location(s) · Alto Neuroscience · NCT06656416
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipola
Phase 3 · 28 location(s) · Xenon Pharmaceuticals Inc. · NCT07172516
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression
NA · 1 location(s) · Sunnybrook Health Sciences Centre · NCT07108257
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Ep
Phase 3 · 81 location(s) · AbbVie · NCT04777357
Brexpiprazole Treatment for Bipolar I Depression
Phase 3 · 3 location(s) · Douglas Mental Health University Institute · NCT04569448
Safety and Feasibility of DBS for Bipolar Depression
NA · 1 location(s) · Icahn School of Medicine at Mount Sinai · NCT07745374
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression a
Phase 2 · 1 location(s) · Joshua Rosenblat · NCT07569198
A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
Phase 3 · 1 location(s) · Korea Otsuka Pharmaceutical Co., Ltd. · NCT03423680
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
NA · 1 location(s) · Peking University · NCT06831435
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