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Study identifier: NCT05977023 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

NMDA Receptor Modulation for the Treatment of Bipolar I Disorder

Condition: Bipolar I Disorder  ·  Sponsor: China Medical University Hospital

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

At present, the treatment of Bipolar I disorder (BD-I), especially its depressive episode (bipolar depression), is still limited, because there is no effective treatment for the associated cognitive impairment and perceived stress. NMDA receptor (NMDAR) dysfunction is associated with BD-I, particularly its cognitive impairment and perceived stress. This study aims to examine the efficacy and safety of an NMDA enhancer (NMDAE) in the treatment of cognitive impairment and perceived stress in the patients with bipolar depression.

This description comes directly from the study's public registry record.

Talk to the study team

Hsien-Yuan Lane Lane, M.D., Ph.D  ·  886 4 22052121  ·  hylane@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Psychiatry, China Medical University HospitalTaichung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT05977023