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Condition: Bipolar I Disorder Synced from ClinicalTrials.gov · July 28, 2026

Recruiting studies: Bipolar I Disorder

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

CLOZAPINE Response in Biotype-1
Phase 4 · 5 location(s) · University of Texas Southwestern Medical Center · NCT04580134A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipola
Phase 3 · 28 location(s) · Xenon Pharmaceuticals Inc. · NCT07172516Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
Phase 2 · 26 location(s) · LB Pharmaceuticals Inc. · NCT07494305Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Phase 3 · 68 location(s) · Intra-Cellular Therapies, Inc. · NCT06372964FOCUS Bipolar: Families Opening Conversations for Understanding Signs
Phase N/A · 1 location(s) · University of Texas Southwestern Medical Center · NCT07622927Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder
Phase 2 · 22 location(s) · Rapport Therapeutics Inc. · NCT07046494A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Phase 3 · 174 location(s) · Bristol-Myers Squibb · NCT06929273Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Type
Phase 3 · 1 location(s) · University of Sao Paulo · NCT07412132SYNCED - SYNChronized Eating in Bipolar Depression Study
NA · 1 location(s) · University of Ottawa · NCT06560957Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
NA · 1 location(s) · Mclean Hospital · NCT06221852Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
Phase N/A · 6 location(s) · Beth Israel Deaconess Medical Center · NCT06740383Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Phase 1 · 5 location(s) · BioXcel Therapeutics Inc · NCT05025605A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Featur
Phase 3 · 104 location(s) · Bristol-Myers Squibb · NCT07140913Cerebellar Modulation of Cognition in Psychosis
NA · 2 location(s) · Mclean Hospital · NCT06107764A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Ep
Phase 3 · 81 location(s) · AbbVie · NCT04777357Melatonin and Response to Lithium
Phase N/A · 1 location(s) · Assistance Publique - Hôpitaux de Paris · NCT05878730A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed
Phase 1/Phase 2 · 1 location(s) · Alzamend Neuro, Inc. · NCT07540338NMDA Receptor Modulation for the Treatment of Bipolar I Disorder
Phase 2 · 1 location(s) · China Medical University Hospital · NCT05977023Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I
Phase 3 · 47 location(s) · Alkermes, Inc. · NCT05303064Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipol
Phase 2 · 49 location(s) · AbbVie · NCT07220460ALTO-100 in Bipolar Disorder With Depression (BD-D)
Phase 2 · 27 location(s) · Alto Neuroscience · NCT06656416Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
NA · 1 location(s) · Peking University · NCT06831435Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
NA · 1 location(s) · KU Leuven · NCT07211750Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
Phase 4 · 9 location(s) · Vanda Pharmaceuticals · NCT05648591LHC-CIDI-5 in Hong Kong
Phase N/A · 1 location(s) · The University of Hong Kong · NCT06804525Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
NA · 4 location(s) · University of California, Los Angeles · NCT06920940Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression
NA · 1 location(s) · Sunnybrook Health Sciences Centre · NCT07108257Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Phase 2 · 1 location(s) · Medical University of South Carolina · NCT05064319Biocollection on Peripheral Inflammation
Phase N/A · 1 location(s) · Nantes University Hospital · NCT05934474Exercise and Olanzapine-samidorphan
Phase 4 · 1 location(s) · New York State Psychiatric Institute · NCT06740890
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.