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Study identifier: NCT07220460 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

Condition: Bipolar I or II Disorder  ·  Sponsor: AbbVie

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population in the United States. The purpose of this study is to assess how safe and effective ABBV-932 is in treating participants with depressive episodes associated with bipolar I or II disorder. ABBV-932 is an investigational drug being developed for the treatment of depressive episodes in adult participants with bipolar I or II disorder. Participants with bipolar I or II disorder who are currently experiencing a depressive episode will enter the study and be treated with open-label ABBV-932. Approximately 200 adult participants with bipolar I or II disorder will be enrolled in approximately 50 sites in the United States and Puerto Rico. Participants will receive oral capsules of ABBV-932 for a 26-week treatment period. The treatment period will be followed by a safety follow-up (SFU) period of 30 days. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regularly scheduled visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (49)

Ima Clinical Research Phoenix (Alea) /ID# 278047Phoenix, Arizona, United StatesRecruiting
Advanced Research Center /ID# 273474Anaheim, California, United StatesRecruiting
Axiom Research /ID# 273482Colton, California, United StatesRecruiting
Collaborative Neuroscience Research - Garden Grove /ID# 273492Garden Grove, California, United StatesRecruiting
Sun Valley Research Center /ID# 273472Imperial, California, United StatesRecruiting
Synergy San Diego /ID# 278340Lemon Grove, California, United StatesRecruiting
Alliance for Research Alliance for Wellness /ID# 273477Long Beach, California, United StatesRecruiting
Nrc Research Institute - Los Angeles /ID# 278450Los Angeles, California, United StatesRecruiting
Excell Research /ID# 273483Oceanside, California, United StatesRecruiting
Inland Psychiatric Medical Group /ID# 273471Temecula, California, United StatesRecruiting
Sunwise Clinical Research /ID# 278165Walnut Creek, California, United StatesRecruiting
Connecticut Clinical Research - Cromwell /ID# 278116Cromwell, Connecticut, United StatesRecruiting

+ 37 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07220460